Autoimmune Thyroiditis and Myasthenia Gravis
نویسندگان
چکیده
منابع مشابه
Autoimmune Thyroiditis and Myasthenia Gravis
Autoimmune diseases (AIDs) are the result of specific immune responses directed against structures of the self. In normal conditions, the molecules recognized as "self" are tolerated by immune system, but when the self-tolerance is lost, the immune system could react against molecules from the body, causing the loss of self-tolerance, and subsequently the onset of AID that differs for organ tar...
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Autoimmune Myasthenia Gravis (MG) is a unique disease among all autoimmune disorders in two ways. First, there are a wide range of sub-specialties involved in the diagnosis and management of MG; secondly MG is an autoimmune disorder whose autoimmunity is well established. In this paper I will cover these topics: history and epidemiology of MG followed by a brief overview on physiology of neurom...
متن کاملExperimental autoimmune myasthenia gravis.
Injection of animals with purified acetylcholine receptor in complete Freund's adjuvant causes development of antibodies which crossreact with receptors in muscle. The crossreacting antibodies impair neuromuscular transmission. Animals with experimental autoimmune myasthenia gravis (EAMG) are excellent models for studying the complex mechanisms by which the autoimmune response to receptor in my...
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Myasthenia gravis (MG) is an autoimmune disorder characterized by weakness and fatigability of skeletal muscles. Erythropoietin (EPO) is a cytokine required to maintain erythroid cells. Recombinant human EPO (rHuEPO) was found to act also on immune cells. Beneficial effects of rHuEPO therapy have been demonstrated in several experimental autoimmune models. We have tested the effect of rHuEPO on...
متن کاملAcquired autoimmune myasthenia gravis - Heterogenous entity
Acquired autoimmune myasthenia gravis (MG) is an organ specific autoimmune disorder of the neuromuscular junction. In the majority of the patients (~85%) antibodies are directed to muscle postsynaptic nicotinic acetylcholine receptor (AChR), but in others the target is non-AChRprotein at neuromuscular junction, such as Muscle-specific receptor tyrosine kinase (MuSK), or low density lipoprotein ...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2017
ISSN: 1664-2392
DOI: 10.3389/fendo.2017.00169